Maricopa Community Colleges  HCR240   20002-20052 
Official Course Description: MCCCD Approval: 12/14/99
HCR240 20002-20052 LEC 4 Credit(s) 4 Period(s)
Human Pathophysiology
Chemical, biological, biochemical, and psychological processes as a foundation for the understanding of alterations in health. The structural and functional pathophysiology of alterations in health; selected therapeutics considered. Prerequisites: BIO202 or equivalent.
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MCCCD Official Course Competencies:
HCR240   20002-20052 Human Pathophysiology
1. Utilize medical terminology as it applies to the pathophysiologic basis for alterations in health. (I-XVI)
2. Demonstrate knowledge of the mechanisms of normal anatomic structure, physiological function, and biochemical processes within the human body. (II-XVI)
3. Demonstrate knowledge of the mechanisms of altered anatomic structure and physiological function within the human body. (II-XVI)
4. Explain signs and symptoms of diseases and their relationship to specific pathophysiological changes in the human body. (II- XVI)
5. Describe the relationships between basic pathophysiology and selected diagnostic and therapeutic modalities. (II-XVI)
6. Explain the basis for actions that could be taken to avoid pathophysiologic states or conditions or to reduce the risks of occurrence of pathophysiologic states or conditions. (II- XVI)
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MCCCD Official Course Outline:
HCR240   20002-20052 Human Pathophysiology
    I. Overview of Pathophysiology: Review of Biochemical Foundations of Health and Illness
      II. Altered Development
          A. Concepts of altered health in children
          B. Concepts of altered health in older adults
        III. Alterations in Cell Function and Growth
            A. Cell and tissue characteristics
            B. Cellular adaptation, injury and death
            C. Wound healing
            D. Genetic and congenital disorders
            E. Alterations in cell differentiation
          IV. Alterations in Body Differentiations
              A. Stress and adaptation
              B. Infectious processes
              C. Inflammation and repair
              D. The immune response
              E. Psychoneuroimmunology
              F. The blood coagulation response
            V. Alterations in Body Fluids
                A. Body fluids and electrolytes
                B. Distribution of fluids
                C. Acid-base balance
              VI. Alterations in Respiratory Function
                  A. Respiratory tract infection, neoplasms and childhood disorders
                  B. Alteration in ventilation and gas exchange
                VII. Alterations in Musculoskeletal Function
                    A. Trauma and infection
                    B. Congenital disorders, metabolic bone disease, neoplasms
                    C. Rheumatic disorders
                  VIII. Alterations in Special Senses
                      A. Vision
                      B. Hearing and vestibular function
                    IX. Alterations in Integumentary Function
                        A. Skin disorders
                        B. Nevi and skin cancer
                        C. Burns
                        D. Age-related skin manifestations
                      X. Alterations in Hemopoietic Function
                          A. Alterations in homeostasis
                          B. Alterations in oxygen transport
                          C. Disorders of white blood cells and lymphoid tissue
                        XI. Alterations in Circulatory Function
                            A. Alterations in blood flow
                            B. Alterations in blood pressure
                            C. Alterations in cardiac function
                            D. Heart failure and shock
                            E. Disorders of cardiac conduction and rhythm
                          XII. Alterations in Gastrointestinal Function
                              A. Alterations in nutrition
                              B. Disorders of the esophagus, stomach, small and large intestine, and peritoneum
                              C. Hepatobiliary system and exocrine pancreas
                            XIII. Alterations in Renal Function
                                A. Functional disorders
                                B. Renal failure
                                C. Alterations in urinary elimination
                              XIV. Alterations in Neurological Function
                                  A. Disorders of brain function
                                  B. Alterations in motor functions
                                  C. Somatosensory function and pain
                                  D. Neurobiology of psychological illness
                                XV. Alterations in Endocrine Function
                                    A. Alterations in endocrine control of growth and metabolism
                                    B. Diabetes mellitus
                                  XVI. Alterations in Reproductive System
                                      A. Alterations in structure/function of male genitourinary system
                                      B. Alterations in structure/function of female genitourinary reproductive systems
                                      C. Sexually transmitted disease
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