Maricopa Community Colleges  MRT241   19954-20032 
Official Course Description: MCCCD Approval: 04/22/03
MRT241 19954-20032 LEC 3 Credit(s) 3 Period(s)
Advanced Radiation Physics and Biology
Advanced physical concepts including x-ray generation, spectrum, imaging, and recording of the radiographic image. Basic principles, genetic effects, and gross effects on the human body related to radiation biology. Prerequisites: MRT151.
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MCCCD Official Course Competencies:
 
MRT241   19954-20032 Advanced Radiation Physics and Biology
1. Explain the physical characteristics of a diagnostic x- ray beam including x-ray generation and the factors affecting the emission spectrum. (I)
2. Explain the physical interaction of radiation with matter including absorption, contrast examinations and attenuation. (II)
3. Describe the factors that determine beam quantity and quality to include half-value layer. (III)
4. Describe the principles of radiation biology in terms of its potential effects on tissues, organs and systems. (IV, V)
5. Describe dose-related effects of radiation in terms of genetic effects and gross effects on the human body. (VI, VII)
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MCCCD Official Course Outline:
 
MRT241   19954-20032 Advanced Radiation Physics and Biology
    I. X-ray Production
        A. Electron-target interaction
        B. X-ray emission spectrum
        C. Factors affecting the x-ray emission spectrum
      II. X-ray Interaction with Matter
          A. Five basic interactions
          B. Differential absorption
          C. Contrast examinations
          D. Exponential attenuation
        III. X-ray emission
            A. Quantity
            B. Quality
          IV. Fundamental Principles of Radiobiology
              A. Human biology
              B. Law of Gergonie' and Tribondeau
              C. Physical factors affecting radiosensitivity
              D. Biologic factors affecting radiosensitivity
              E. Radiation dose-response relationships
            V. Molecular and Cellular Radiobiology
                A. Irradiation macromolecules
                B. Radiolysis of water
                C. Direct and indirect effect
                D. Target theory
                E. Cell survival kinetics
                F. Linear Energy Transfer (LET), Relative Biologic Effectiveness (RBE), and Oxygen Enhancement Ratio (OER)
              VI. Early effects of radiation
                  A. Acute radiation lethality
                  B. Local tissue damage
                  C. Hematologic effects
                  D. Cytogenetic effects
                VII. Late effects of radiation
                    A. Local tissue effects
                    B. Life span shortening
                    C. Risk estimates
                    D. Radiation-induced malignancy
                    E. Total risk of malignancy
                    F. Radiation and pregnancy
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