Maricopa Community Colleges  RES134   20002-20075 
Official Course Description: MCCCD Approval: 12/14/99
RES134 20002-20075 LEC 1 Credit(s) 1 Period(s)
Advanced Respiratory Care Pharmacology
Pharmalogic principles specific to the respiratory care practitioner. Information on specific drugs to include general drug information, side effects, and respiratory care considerations. Administration of topical anesthetics. Non-respiratory drugs that effect ventilation.
Prerequisites: Admission into the Respiratory Care program. Corequisites: HCC164.
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MCCCD Official Course Competencies:
 
RES134   20002-20075 Advanced Respiratory Care Pharmacology
1. Review basic pharmalogic principles. (I)
2. Given a patient with bronchial smooth muscle abnormality, administer pharmacological agents. (II)
3. Given a patient with respiratory infection, identify appropriate antimicroial therapy. (III)
4. Administer topical anesthetics. (IV)
5. Describe the non respiratory drugs which effect ventilation. (V)
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MCCCD Official Course Outline:
 
RES134   20002-20075 Advanced Respiratory Care Pharmacology
    I. Pharmacologic Principles
        A. Competitive antagonism
        B. Noncompetitive antagonism
        C. Absorption and degradation
      II. Bronchial Smooth Muscle Abnormality
          A. Review of autonomic nervous system
            1. sympathetic
            2. parasympathetic
          B. Adrenergic receptors and Amines
            1. chemistry
            2. alpha and beta activity
            3. receptor selectivity
            4. adrenergic activity/beta carbon substituents
            5. adrenergic activity/alpha carbon substituents
            6. amine structure and alpha and beta activity
            7. amine structure and beta 1 and beta 2 receptor selectivity
          C. Muscarinic Antagonists
            1. action
            2. rationale
            3. diagnostic use
          D. Airway mediators
            1. histamine
              a. synthesis, release, and metabolism
              b. action
              c. release during allergic response
              d. diagnostic use
              e. agents used for protection against histamine induced reversible airway disease
            2. Prostaglandins
              a. chemistry, synthesis, and inactivation
              b. effects in the lungs
              c. factors governing release in the lung
              d. prostaglandins as therapeutic agents
          E. Bronchodilators
            1. sympathomimetics
            2. parasympatholytic
            3. xanthines
          F. Corticosteroids
            1. structure and metabolism
            2. mechanics of action
            3. adverse effects
            4. administration
        III. Antimicrobial Agents
            A. Principles
              1. antimicrobial therapy
              2. identification of pathogens
              3. modes of action
              4. microbial resistance
              5. superinfections
              6. routes of administration
            B. Treatment of Pulmonary Infections
              1. penicillins
              2. cephalosporins
              3. aminoglcosides
              4. tetracuclines
              5. sulfonamides
              6. chloramphenicol
              7. polymyxin B
              8. erythromycin
              9. clindamycin
              10. antifungal
              11. antituberculosis
          IV. Topical Anesthetics
              A. Dosage
              B. Side effects
            V. Non Respiratory Drugs which affect Ventilation
                A. Neuromuscular blocking agents
                  1. nondepolarizing
                  2. depolarizing
                B. Diuretics
                  1. action
                  2. effects
                  3. therapeutic uses
                  4. types
                C. Agents affecting the central nervous system
                  1. central nervous system
                  2. narcotics and non narcotics
                  3. narcotics antagonists
                  4. sedative/hypnotics
                  5. antipsychotic tranquilizers
                D. Respiratory stimulants
                E. Agents affecting the Cardiovascular system
                  1. inotrophic
                  2. antiarrythmic
                  3. antianginal
                  4. calcium- channel blockers
                  5. beta blockers
                  6. alpha agonists
                  7. angiotensin converting enzymes
                  8. drugs affecting the blood
                    a. anticoagulants
                    b. thrombolytics
                    c. others
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