Maricopa Community Colleges  HCE245   20062-99999 

Official Course Description: MCCCD Approval: 11-22-2005

HCE245  2006 Spring – 2011 Summer II

LAB  1.0 Credit(s)  6.0 Period(s)  Load 0.0  Occ

Practicum: Clinical Immunohematology and Immunology

Practicum in immunohematology and immunology in healthcare facilities or reference laboratories. Performance of clinical skills in immunity and immunologic testing, testing for disorders of the immune system, blood group antigens, antibodies, and genetics. Observation of donor blood collection, component preparation, and transfusion therapies. Performance of testing techniques and evaluation of data.

Prerequisites: Acceptance into the Clinical Laboratory Sciences program or permission of the Program Director.

 

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MCCCD Official Course Competencies:

 

 

HCE245  2006 Spring – 2011 Summer II

Practicum: Clinical Immunohematology and Immunology

 

1.

Apply the fundamental characteristics and principles of the immune response. (I)

2.

Use and apply the principles and performance of immunologic tests. (II)

3.

Apply testing techniques for disorders of the immune system, tumor associated antigens, viral infections, and hypersensitivity. (III)

4.

Apply the principles of blood group genetics. (IV)

5.

Apply the principles for the recognition and differentiation of blood group antigens and antibodies. (V)

6.

Observe the principles and testing associated with donor blood collection and component preparation. (VI)

7.

Observe the principles and testing associated with transfusion therapies. (VII)

8.

Perform testing procedures of immunology and immunohematology. (VIII)

9.

Evaluate data to interpret test results. (VIII)

 

 

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MCCCD Official Course Outline:

 

 

HCE245  2006 Spring – 2011 Summer II

Practicum: Clinical Immunohematology and Immunology

 

I. Body Defenses: Resistance to Disease

A. Natural immunity

1. Major components

2. Other factors

B. Acquired immunity

1. Active immunity

2. Passive immunity

C. Cell mediated immunity

D. Antibody mediated immunity

1. Antigen molecules

2. Immunoglobulins

E. Complement system

II. Immunologic Testing

A. Agglutination methods

B. Electrophoresis techniques

C. Immunoassay labeling

III. Defects and Disorders of the Immune System

A. Autoimmune diseases

B. Tumor associated antigens

C. Immunodeficiencies

D. Phagocyte deficiencies

E. Complement deficiencies

F. Viral infections

G. Hypersensitivity

H. Other

IV. Blood Group Genetics

A. Inheritance

B. Blood group antigens

C. Blood group immunology

V. Detection and Identification of Blood Group Antigens and Antibodies

A. Carbohydrate based

B. Polypeptide based

VI. Donor Collections and Component Preparation

A. Donor interview

B. Whole blood collections

1. Red cells

2. Plasma

3. Cryoprecipitate

4. Platelets

C. Apheresis collections

D. Testing

VII. Transfusion Therapies

A. Indications and component selection

B. Pretransfusion testing

C. Adverse effects

VIII. Testing and Results

A. Flocculation

B. Latex agglutination

C. Direct bacterial agglutination

D. Hemagglutination

1. Direct

2. Indirect

3. Inhibition

E. Quality control and quality assurance

F. Review of other techniques

1. Electrophoresis

2. Immunoassay

3. Molecular

4. Automated

 

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