Maricopa Community Colleges  HCE244   20062-99999 

Official Course Description: MCCCD Approval: 11-22-2005

HCE244  2006 Spring – 2011 Summer II

L+L  6.0 Credit(s)  9.0 Period(s)  8.1 Load  Occ

Clinical Immunohematology and Immunology

Principles of immunity and immunologic testing. Causes of disorders of the immune system. Study of blood group antigens, antibodies, and genetics. Understanding of donor blood collection, component preparation, and transfusion therapies. Performance of testing techniques and evaluation of data.

Prerequisites: Acceptance into the Clinical Laboratory Sciences program or permission of the Program Director.

 

Go to Competencies   Go to Outline
 

MCCCD Official Course Competencies:

 

 

HCE244  2006 Spring – 2011 Summer II

Clinical Immunohematology and Immunology

 

1.

Distinguish between the fundamental characteristics and principles of the immune response. (I)

2.

Differentiate between the principles and performance of immunologic tests. (II)

3.

Differentiate disorders of the immune system, tumor associated antigens, viral infections, and hypersensitivity. (III)

4.

Distinguish among the principles of blood group genetics. (IV)

5.

Integrate the principles for the recognition and differentiation of blood group antigens and antibodies. (V)

6.

Describe the principles and testing associated with donor blood collection and component preparation. (VI)

7.

Distinguish between the principles and testing associated with transfusion therapies. (VII)

8.

Perform testing procedures of immunology and immunohematology. (VIII)

9.

Interpret, evaluate, and report test results. (VIII)

 

 

Go to Description    Go to top of Competencies
 

MCCCD Official Course Outline:

 

 

HCE244  2006 Spring – 2011 Summer II

Clinical Immunohematology and Immunology

 

I. Body Defenses: Resistance to Disease

A. Natural immunity

1. Major components

2. Other factors

B. Acquired immunity

1. Active immunity

2. Passive immunity

C. Cell mediated immunity

D. Antibody mediated immunity

1. Antigen molecules

2. Immunoglobulins

E. Complement system

II. Immunologic Testing

A. Agglutination methods

B. Electrophoresis techniques

C. Immunoassay labeling

III. Disorders of the Immune System

A. Autoimmune diseases

B. Tumor associated antigens

C. Immunodeficiencies

D. Phagocyte deficiencies

E. Complement deficiencies

F. Viral infections

G. Hypersensitivity

H. Other

IV. Blood Group Genetics

A. Inheritance

B. Antigens

C. Immunology

V. Detection and Identification of Blood Group Antigens and Antibodies

A. Carbohydrate based

B. Polypeptide based

VI. Donor Collections

A. Interview

B. Component preparation

1. Red cells

2. Plasma

3. Cryoprecipitate

4. Platelets

C. Apheresis collections

D. Testing

VII. Transfusion Therapies

A. Indications and component selection

B. Pretransfusion testing

C. Adverse effects

VIII. Testing and Results

A. Flocculation

B. Latex agglutination

C. Direct bacterial agglutination

D. Hemagglutination

1. Direct

2. Indirect

3. Inhibition

E. Quality control and assurance

F. Review of other techniques

1. Electrophoresis

2. Immunoassay

3. Molecular

4. Automated

 

Go to Description    Go to top of Competencies    Go to top of Outline