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Official Course
Description: MCCCD Approval: 5-27-1997 |
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BIO241
1998 Spring – 2008 Summer
II |
LEC 4.0 Credit(s) 3.0 Period(s) 3.0 Load Acad LAB 0.0
Credit(s) 3.0 Period(s) 2.4 Load |
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Human
Genetics |
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An
introduction to the basic concepts of human heredity and cytogenetics
including Mendelian, molecular, and population
genetics. Prerequisites: BIO100, or BIO181, or
equivalent, or permission of Instructor. |
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Go to Competencies Go to Outline
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MCCCD
Official Course Competencies: |
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BIO241 1998
Spring – 2008 Summer II |
Human Genetics |
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1.
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Describe the major contributions to the development of
human genetics. (I) |
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2.
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Define terms used inhuman genetics. (II) |
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3.
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Contrast between the major modes of monogenic inheritance.
(III) |
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4.
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Describe the mechanics of cell division. (IV) |
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5.
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Describe the biochemical nature of genes and chromosomes.
(IV) |
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6.
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Describe recombinant DNA technology. (IV) |
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7.
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Describe how numerical and structural chromosome
abnormalities arise. (IV) |
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8.
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Describe the nature and causes of mutation. (IV) |
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9.
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Describe the basic tenets of multigenic
inheritance. (V) |
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10.
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Describe the underlying principles of population genetics.
(VI) |
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11.
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Describe the importance of prenatal diagnostic techniques
in genetic counseling. (VII) |
Go to Description Go to top of Competencies
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MCCCD
Official Course Outline: |
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BIO241 1998
Spring – 2008 Summer II |
Human Genetics |
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I. History of the
Development of Human Genetics II. Terminology of Human
Genetics III. Principles of Mendelian Genetics A. Autosomal
recessive B. Autosomal
dominant C. X-linked recessive D. X-linked dominant E. Y-linked IV. Chromosomes and Genes A. Physical basis of
inheritance B. Chemical nature of genes
and chromosomes 1. Replication,
transcription, and translation 2. Recombinant DNA
technology C. Mitosis D. Meiosis and gamete
formation E. Gene mapping F. Expression of genes and
regulation of expression G. Numerical chromosomal
abnormalities H. Structural chromosomal
abnormalities I. Mutation J. Karyotyping
K. Biochemical genetics 1. Metabolic disorders 2. Amniocentesi:
screen for enzymes L. Genetics of the immune
system 1. Blood groups 2. Histocompatibility
and the HLA system 3. Antibody formation 4. Autoimmune disorders V. Polygenic Traits VI. Genes in Populations A. Gene frequencies B. Genotype frequencies C. Calculation of gene
frequencies D. Hardy-Weinburg equilibrium VII. Availability of
Prenatal Diagnostic Techniques A. Amniocentesis B. Chorionic villi analysis C. Use of DNA probes |