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Official Course
Description: MCCCD Approval: 05/27/97 |
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BIO080AU
1998 Spring – 2012 Fall |
LEC |
4 Credit(s) |
3 Period(s) |
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Basic
Concepts of Human Genetics |
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Corresponds
to BIO241 Human Genetics. Enrollment recommended if student performance
inadequate in BIO241. Prerequisites: None. |
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Go to Competencies Go to Outline
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MCCCD
Official Course Competencies: |
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BIO080AU 1998
Spring – 2012 Fall |
Basic Concepts of Human Genetics |
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1.
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Describe the major contributions to the development of
human genetics. (I) |
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2.
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Define terms used inhuman genetics. (II) |
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3.
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Contrast between the major modes of monogenic inheritance.
(III) |
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4.
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Describe the mechanics of cell division. (IV) |
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5.
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Describe the biochemical nature of genes and chromosomes.
(IV) |
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6.
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Describe recombinant DNA technology. (IV) |
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7.
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Describe how numerical and structural chromosome
abnormalities arise. (IV) |
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8.
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Describe the nature and causes of mutation. (IV) |
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9.
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Describe the basic tenets of multigenic
inheritance. (V) |
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10.
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Describe the underlying principles of population genetics.
(VI) |
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11.
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Describe the importance of prenatal diagnostic techniques
in genetic counseling. (VII) |
Go to Description Go to top of Competencies
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MCCCD
Official Course Outline: |
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BIO080AU 1998
Spring – 2012 Fall |
Basic Concepts of Human Genetics |
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I. History of the
Development of Human Genetics II. Terminology of Human
Genetics III. Principles of Mendelian Genetics A. Autosomal recessive B. Autosomal dominant C. X-linked recessive D. X-linked dominant E. Y-linked IV. Chromosomes and Genes A. Physical basis of
inheritance B. Chemical nature of genes
and chromosomes 1. Replication,
transcription, and translation 2. Recombinant DNA
technology C. Mitosis D. Meiosis and gamete
formation E. Gene mapping F. Expression of genes and
regulation of expression G. Numerical chromosomal
abnormalities H. Structural chromosomal
abnormalities I. Mutation J. Karyotyping K. Biochemical genetics 1. Metabolic disorders 2. Amniocentesi:
screen for enzymes L. Genetics of the immune
system 1. Blood groups 2. Histocompatibility and
the HLA system 3. Antibody formation 4. Autoimmune disorders V. Polygenic Traits VI. Genes in Populations A. Gene frequencies B. Genotype frequencies C. Calculation of gene
frequencies D. Hardy-Weinburg equilibrium VII. Availability of
Prenatal Diagnostic Techniques A. Amniocentesis B. Chorionic villi analysis
C. Use of DNA probes |