Official Course Description: MCCCD Approval: 07/22/08
BIO218 19956-20086	LEC	4 Credit(s)	4 Period(s)
Pathophysiology
Biology course with emphasis on the physiologic and biologic manifestations of disease. Includes concepts in the sciences and exploring how alterations structure (anatomy) and functions (physiology) disrupt the human body as a whole. Prerequisites: BIO201, BIO202, BIO205, CHM151 and CHM152 or permission of Instructor.

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MCCCD Official Course Competencies:
BIO218   19956-20086	Pathophysiology

1.	Describe normal and altered cellular functions and processes. (I)
2.	Describe normal and altered development. (II)
3.	Describe normal and altered fluid and electrolyte balance. (III)
4.	Describe normal and altered mechanisms of immunity and inflammation. (IV)
5.	Describe normal and altered function of the Hematologic System. (V)
6.	Describe normal and altered functions of the Cardiovascular and Lymphatic Systems. (VI)
7.	Describe normal and altered functions of the Pulmonary System. (VII)
8.	Describe normal and altered function of the Renal and Urologic Systems. (VIII)
9.	Describe normal and altered function of the Endocrine System. (IX)
10.	Describe normal and altered function of the Digestive System. (X)
11.	Describe normal and altered functions of the Musculoskeletal System. (XI)
12.	Describe normal and altered functions of the Integumentary System. (XII)
13.	Describe normal and altered functions of the Neurologic System. (XIII)
14.	Describe normal and altered functions of the Reproductive System. (II, XIV)

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MCCCD Official Course Outline:
BIO218   19956-20086	Pathophysiology

I. Cellular Dynamics A. Cells 1. Structure 2. Function 3. Organization B. Alterations in Cellular Processes C. Genetic Disorders II. Development A. Biophysical Development 1. Reproduction 2. Children B. Biophysical developmental changes of adults C. Biophysical changes of the older adult III. Fluids, Electrolyte, Acid-base, Nutritional balance, and Shock A. Fluid and Electrolyte balance 1. Normal 2. Altered B. Acid-base balance 1. Normal 2. Altered C. Nutritional balance 1. Normal 2. Altered D. Shock IV. Bodily defense mechanisms A. Inflammation and Repair B. Immunity C. Neoplasia V. Hematology A. Erythrocyte function 1. Normal 2. Altered B. Leukocyte function 1. Normal 2. Altered C. Coagulation 1. Normal 2. Altered VI. Circulation A. Normal circulatory dynamics B. Alterations in cardiac rhythms C. Compromised pumping ability of the heart D. Alteration in specific structures in the heart E. Hypertension F. Alteration in systemic circulation VII. Respiration A. Normal respiratory function B. Pulmonary functions 1. Restrictive Alterations 2. Obstructive Alterations C. Other alterations affecting the pulmonary system VIII. Urinary excretion A. Normal renal and urinary excretory functions B. Immunologic, infection, toxic, and other alteration in function C. Disorders in micturition and obstruction of the genitourinary tract D. Renal failure and uremia IX. Endocrine Regulation A. Pituitary regulation and alterations in function B. Adrenal mechanisms and alterations C. Thyroid and parathyroid functions and alterations D. Normal and altered function of the pancreas X. Digestion, Absorption, and use of food A. Gastrointestinal system 1. Normal 2. Altered B. Normal hepatobiliary and pancreatic exocrine function C. Alterations in hepatobiliary functions XI. Musculoskeletal function A. Muscular System 1. Normal 2. Altered B. Skeletal system 1. Normal structure and function 2. Altered structure and functions XII. Protective covering of the body A. Skin 1. Normal structure and function 2. Alterations of structure and function B. Other XIII. Neural Control A. Normal structure and function of the central and peripheral nervous systems B. Adaptations and alterations on the special senses C. Common adaptations and alterations in higher neuralgic functions D. Pain E. Traumatic alterations in the nervous system F. Tumors and infections in the central nervous system G. Degenerative and chronic alterations in the nervous system XIV. Reproduction A. Male reproduction function 1. Normal 2. Altered B. Female reproductive function 1. Normal 2. Altered C. Sexually transmitted diseases

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